I've noticed that when I download files from netload.in via my work connection (Vodafone ADSL) I get much faster speeds than when I do the same at home (TelstraClear ADSL).  At work I get 200KB/s and at home I get about 20KB/s (up to 50KB/s if I'm lucky).

I know that factors such as time of day will affect download speeds, but is it possible for two ISP's to have different routes to a site and one route is faster than another?

My connection at home can achieve 200KB/s downloads from other sites, so I don't think it's anything on my end.

A tracert from work looks like this:

Tracing route to www.netload.in [85.131.244.110]
over a maximum of 30 hops:

1 <1 ms <1 ms <1 ms RTA1025W.home [192.168.1.1]
2 20 ms 18 ms 20 ms be2-100.bras2ftc.akl.vf.net.nz [203.109.130.162]
3 17 ms 17 ms 17 ms be9-100.ppnzftc01.akl.vf.net.nz [203.109.130.161]
4 18 ms 18 ms 17 ms be7-188.ppnzftc02.akl.vf.net.nz.180.109.203.in-addr.arpa [203.109.180.226]
5 20 ms 22 ms 18 ms be8-188.ppnzftc02.akl.vf.net.nz.180.109.203.in-addr.arpa [203.109.180.225]
6 145 ms 144 ms 147 ms ten-0-2-0-100.bdr02.sjc01.ca.VOCUS.net [114.31.199.141]
7 147 ms 164 ms 144 ms 10gigabitethernet3-2.core1.sjc1.he.net [64.71.184.45]
8 138 ms 146 ms 149 ms 10gigabitethernet2-1.core1.sjc2.he.net [72.52.92.118]
9 214 ms 237 ms 214 ms 10gigabitethernet9-1.core1.nyc4.he.net [184.105.213.174]
10 281 ms 291 ms 281 ms 10gigabitethernet1-2.core1.lon1.he.net [72.52.92.242]
11 293 ms 299 ms 299 ms 10gigabitethernet1-1.core1.ams1.he.net [72.52.92.82]
12 * * * Request timed out.
13 319 ms 295 ms 296 ms www.netload.in [85.131.244.110]

I'll do the same from home tonight and post the results here.