OK so I have built my pc and its running on onboard graphics atm and am now about to purchase a 7850 , I did contemplate the 560 ti superclocked but I think this card will go nicely , all my other specs are above par but just incase people would like to know, asus p8 z77 mobo , intel i5 3570k cpu , 8gb corsair vengeance RAM , 600watt psu.
Now I sw the asus 7850 for $420 so i have saved and can now afford that , bu then i came across the sapphire version of the card for about $360.
So my question is , what am I losing/gaining by purchasing one card over the other
If you don't plan to overclock the cards, go with the Sapphire. (i.e. there isn't much difference).
If you plan on overclocking the cards, read up on different maker round ups and consider whether it's actually worth spending a bit more for probably slightly more stable components, and possibly a larger fan (vs. for instance, buying the 7870 or 7950 or nVidia competition).
Had a quick look on a price comparison website
Edit: If you're on a budget I think Powercolor is the cheapest brand, I haven't used them myself but I've heard murmurings of them being not as good - difficult to get good stats on whether that's true or not though.