I have been very very happy with the A800 Panasonics. As a big headphone and good sound guy, These are pretty incredibly sounding for something with more than half decent ANC.
It's not perfect, I don't really like the button controls, I wish they were entirely gesture controlled like the Sony XM4's, or that the buttons were a bit more distinguishable from each other to make controlling them easier, but in terms of comfort, sound quality and ANC, I haven't found a better combination yet. I haven't tried the XM5's but ruled them out as they don't fold up, and I haven't tried the 45's from Bose.