If something specific is wrong then its much better trying to diagnose rather than getting a ‘fixit’ program.
I don't recommend registry cleaning after Windows XP where it was already difficult to show a real benefit. Registry management is much improved since then so I doubt you could show any significant benefit except by forcing an unusual configuration such as using less RAM than the specified Windows systems requirements.
Reg cleaning does nothing.
That comment needs some qualifying.
Registry cleaning was essential last century. For example, back when the registry file had a maximum size which was easily reached. I remember manual editing to reduce registry size being difficult, time-consuming and very risky so registry cleaners were really helpful in speeding up that activity.
21st century Windows systems only show a performance benefit in scenarios with severely constrained resources that approach one of Windows hard memory limits, like exhausting desktop heap in the WIN32 subsystem or creating a large non-paged pool.
Thanks for all the responses folks. As always there are a number of opinions, all credible. I will rely on Storage Sense and not bother with registry cleaning.