* The lack of a back button. Most apps put a back button at the top-left corner of the screen, but you only ever hit the home button to jump out of an app. My wife still tries to hit the non-existent back button every now and again.
* File management is a pain. iOS fences of every app into its own area, and there is no way for apps to send files between each other. About the only shared space is the photo roll and that is only allowed to store photos and videos. You have to use iTunes to load files for individual apps. It's possible to use non-Apple software like MediaMonkey to send content to the iPad, but it's not always reliable and is limited to the media types that the iPad supports with its built-in apps.
* The notification bar has its good and bad points. It's good in that you can access it at all times, even in full-screen apps. But when you do access it, it's very narrow, taking up only about half the width of the screen in portrait mode. Getting rid of items takes 2 taps instead of Androids sideways swipe. One thing that Android could borrow is the ability to control notifications on a per-app basis. You can stop an app from showing notifications at all, remove the notification sound, add it as a badge on the lock screen, or make it pop up in the middle of whatever you're doing.
* If you actually use home screen widgets, you'll miss them. My wife uses calendar and weather widgets on her phone, and has to find and start an app on the iPad.
* Setting up your apps can be a pain if they have logins. There is no sharing of account data, so you have to enter your credentials separately for every app. You don't know how annoying this is until you set up Gmail, G+, Google Drive, YouTube and Chrome all in a row.
The iPad is by no means a bad device. It's different to Android, but I wouldn't say it was better or worse.
Amusing side-note: My wife is tech-friendly, but not a true geek. After she'd been using the iPad for a week or so I asked what she thought of it. Her response: "I think it'd be more useful if it ran Android."