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A number of preprints make news, and what does not make news often is the RETRACTION.
You need qualified experts to sift wheat from chaff as it were. Some were released with no review at all.
About 154 of them here.
https://retractionwatch.com/retracted-coronavirus-covid-19-papers/
Appears if you put garbage into a meta-analysis you get garbage out. Who knew !
Its been withdrawn for revision due to major flaws in largest most optimistic studies.
https://retractionwatch.com/2021/08/10/ivermectin-meta-analysis-to-be-retracted-revised-say-authors/
Huge study supporting Ivermectin as Covid treatment withdrawn over ethical concerns
https://www.theguardian.com/science/2021/jul/16/huge-study-supporting-ivermectin-as-covid-treatment-withdrawn-over-ethical-concerns
Flawed ivermectin preprint highlights challenges of COVID drug studies
https://www.nature.com/articles/d41586-021-02081-w
Surgisphere who were involved in dubious study on hydroxychloroquine, and an Ivermectin study.
https://www.nature.com/articles/d41586-020-01695-w
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Retracted studies had relied on health-record analyses from a company that declined to share its raw data for an audit.
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Main problem is its being pushed as 100% effective, on shaky evidence, and replacing vaccine that has real efficacy data.
Vaccines we have a mountain of data and oversight and Billions of shots delivered world wide.
Oversight by many leading authorities in Europe, UK, USA, South Korea, Australia, NZ etc, etc, etc
We have data by age, data for delta, data for different countries with different conditions.
Data coming in on 3rd doses, and for children.
Batman: The beta app from the other thread
I'll set answer so you can find it easily
https://app-beta.covid19.health.nz/
Earlier today I went onto the Ministry of Health site via a link I'd been sent to ask for my proof of vaccination. Not sure if the site you've linked accesses the same document or something different.
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Technofreak:
Batman: The beta app from the other thread
I'll set answer so you can find it easily
https://app-beta.covid19.health.nz/
Earlier today I went onto the Ministry of Health site via a link I'd been sent to ask for my proof of vaccination. Not sure if the site you've linked accesses the same document or something different.
The site is different, it allows you to see your vaccination data, ( place time, which arm etc:).. The link you followed is designed to get a letter from MoH for travel...
It looks like the "certificate" will be some form of bar code that can be scanned an verified by a business/event operator....
To be honest it was a none-announcement as we all knew the Govt was going to use/allow certificates, (they have been talking about it for weeks)
What we really want to know is which businesses will be required to use it,
which businesses will not be allowed to use it (likely supermarkets, schools etc)
and which businesses will be able to choose themselves if they want to use it...
( also a couple of interesting quirks came up in the media Q+A.. some people are refusing to allow govt officials OT etc) on their property if the staff are not vaccinated... i'm guessing it won't be lng until someone takes a case saying the police endangered me because the officer wasn't vaccinated)
Does anyone here know how the tradeoff is made by medsafe (or whoever it is) around approving medicines/vaccines accounting for individual risk vs community risk?
The example I am currently interested in: vaccinating children is likely to help stop the spread and impact of covid across the community as a whole. But lets imagine that the risk of (e.g.) sever heart inflammation in the child from a vaccination is x%, but the chance of the child getting critically ill from covid is y%, and x > y, it would seem that the cost outweighs the benefits and on that basis children shouldn't be approved. This is a simplistic example but you'll get the drift.
What I am wondering is whether medicines are approved on a per person calculation basis only, or whether they also account for wider community benefits (less transmission by children for example).
Does anyone know or have any insights?
FWIW, I understand that the clinical trial data that's been submitted to the US FDA as part of the approval process for gaining an emergency use authorisation for 5-11 yo's showed zero cases of heart inflammation (myocarditis / pericarditis).
But the number of participants in trials was probably too low - way below the incidence rate of myocarditis in the susceptible groups (adolescent and young men) - so if they did have one or two cases - or zero as observed, it's probably not statistically significant.
There's also an inherent problem with the data and assessing myocarditis risk, all side effects from the vaccine are being monitored, but the expected rate of myocarditis / pericarditis in the (pre-covid) community isn't really known. (If symptoms are mild then an unknown number of individuals won't seek medical diagnosis, and even if they do seek medical advice, an unknown number of doctors probably won't even attempt to diagnose it). So if the background incidence is probably higher than reported, thus the risk as a side effect from mRNA vaccines is likely exaggerated during rollout where you're getting high enough numbers to see something which may be statistically significant, but you don't have a double blind placebo group to compare it with.
Anyway, the dose of the Pfizer vaccine in the trials was 2 x 10ug mRNA - 1/3 of the dose given to +12YOs. It showed a very strong immune response. It'll probably be approved with an EUA by FDA, then a panel at Medsafe would review that data and make a decision for here. I hope so.
If it was available and if I had 5-11 yo kids, I'd definitely get them vaxxed. Seems clear now that kids can get pretty sick with delta.
Another important thing about this whole anti-vaxxer movement (as I mentioned in the main covid thread) is the hijacking of the grassroots movement (read conspiracy theorists) by alt-right, neo-nazis and terrorists.
https://institute.global/policy/fringes-forefront-how-far-right-movements-across-globe-have-reacted-covid-19 (which looks into regional movements, including a section on Australia and New Zealand)
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freitasm:
Another important thing about this whole anti-vaxxer movement (as I mentioned in the main covid thread) is the hijacking of the grassroots movement (read conspiracy theorists) by alt-right, neo-nazis and terrorists.
https://institute.global/policy/fringes-forefront-how-far-right-movements-across-globe-have-reacted-covid-19 (which looks into regional movements, including a section on Australia and New Zealand)
My suspicion is the fires are being stoked by some foreign state sponsored actors. You only seem to hear of this stuff occurring in Western democracies.
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