Interesting set of interviews with Trump voters who support his cabinet picks.  The tl;dr is that it's been business as usual / no change in Washington for decades now and anyone the Democrats would have brought in would just perpetuate this (true, look at Biden's record, nothing changed).  So they support Trump's picks because their term will see some change, for the first time in decades:

For Ed Bisch the desire to tear down parts of the system is deeply personal. He lost his 18-year-old son Eddie to a prescription opioid overdose in 2001, an early victim of an epidemic that has claimed close to 900,000 lives. Bisch voted solidly Democratic all the way up to supporting Hillary Clinton in 2016 in the belief that the party would take on the big pharma interests that caused the opioid epidemic. But little changed.

 

Then Bisch saw Trump in office and decided he was the president most likely to challenge the drug industry and what he sees as its corruption of American medicine and health regulation. Bisch is enthusiastic about Kennedy, who is a former heroin addict, and JD Vance as vice-president after he wrote a bestseller, Hillbilly Elegy, about growing up in a region blighted by drugs.