Yes, I'm on Leopard and will be for the life of my mac mini as that is where Front Row ended.
My current version of iTunes (11.2.2) wifi sync does not work and it will crash if I transfer files to the "automatically add directory" via SCP (SMB is fine).
I'm considering upgrading (12.01.26) but was wanting to check with other Leopard users for warnings & gotchas.