He's recently purchased an Asus P7P55D-E Pro mobo, Intel Core i7 #860, 2x Asus 1GB ENGTS250's, 2x 2GB Hynix DDR3-1333 RAM, and an Acbel PSU (900-1000W).
After everything was put together and the usual drivers installed, so far, so good.
But when he rebooted after a normal SLI setup, he started reporting BSoD's, which only seem to go away when run in Safe Mode. He's checked the drivers and the PCI-E brick connectors, updated the mobo firmware, clean re-installed, and the problem still persists. The same issues were present with 2x Asus 1GB EN9800GT's he originally purchased which were later exchanged for the GTS250's.
He appears not to be the only one having these issues, so I can only hazard a guess that there's an engineering/design flaw at play.