"Pros"
Stylish packaging that is concise but sturdy and attractive.
Brilliant design and build quality - feels solid but light, looks amazing.
Near vanilla Android experience, so much better than TouchWiz.
HD displays are great to look at.
Very snappy due to 1.7GHz quad core plus 2GB RAM.
Padfone Infinity and Station firmware updates are prompted and seamless (although one dialog box called it a Padfone 2 station).
"Cons"
Android 4.1.2 at this stage, not 4.2 yet.
Wifi channels 12 & 13 not supported/enabled (Typical, that is what my router had auto set to.)
All in all I am most impressed. There are a few bugs which I have no doubt will be ironed out in due course. Love it!
EDIT: OK so it appears to do apps fine (apart from ASB which is locked to portrait, even though on the handset it does both), it is just Twitter and Facebook make ugly Android tablet apps! Here I was thinking it was just stretching the phone app to fill the screen rather than give me the tablet app, but this is how it is on all Android tablets! Tick that one off :-)
EDIT 2: Showing my Android tablet n00bness here, the ASB and Spotify apps only work in portrait on all Android tablets by the looks. Silly developers but that is less Padfone glitches :-)
EDIT 3: Once past the login screen the ASB app is happy in landscape. Air NZ mPass is portrait only.
EDIT 4: There have been numerous firmware updates over the past couple of weeks, very encouraging and refreshing! They even provide brief changelogs here.