Outside the -70°C transportation box, you have ~4h at +7°C 'til the application (this is for BioNtec).

"[Governor] Stitt declares Thursday statewide day of prayer, fasting for Oklahomans affected by coronavirus"

This will not end well for America. A vaccine better work well, or they are just farked.

 

Gov. Kevin Stitt announced that he is declaring Thursday, Dec. 3 as a statewide day of prayer and fasting for all Oklahomans affected by the COVID-19 pandemic.

 

“Oklahomans have always turned to prayer to guide us through trials and seasons of uncertainty, and I am asking Oklahomans of all faiths and religious backgrounds to join together with me on Thursday,” said Stitt said in a news release. “I believe we must continue to ask God to heal those who are sick, comfort those who are hurting and provide renewed strength and wisdom to all who are managing the effects of COVID-19.”

 

sbiddle:

 

The UK rollout is expected to begin on the 7th and their plans published a week or so ago are still to have the entire country vaccinated by April (first dose completed by the end of January). If this can be pulled off it's going to be one of the best logistics operations of all time!

 

Back of envelope says

66 million ppl over 2 months, = 1 million ppl per day , if there are 1000 vaccination sites, that's 1000 ppl per site/day

There are 1440 minutes in a 24 hr day, so its basically 1000 sites vaccinating  1 person a minute for 2 month solid, then repeat again in Feb/Mar,

If you had 10 vaccinators per site you are down to 100 ppl per day/site .... but you then need 100,000 trained vaccinators.....

They are doable numbers, but the queues would be horrendous ......

Great SCOTT, hes gone ! 

Well the not so great Scott Atlas has left the building.
https://www.thedailybeast.com/trumps-favorite-covid-19-adviser-scott-atlas-resigns-reports?ref=home

""
Scott Atlas, President Trump’s special adviser on COVID-19 who pushed back on lockdowns and repeatedly downplayed the severity of the coronavirus pandemic, has submitted his resignation.

The neuroradiologist, who lacked expertise in infectious disease, began his 130-day position as a special government employee in August, and his gig was set to expire this week.
""

Hmm Resign ? Maybe looking to some future career opportunities where he can disavow his role in the policies, I resigned after all. 

ezbee:

 

Great SCOTT, hes gone ! 

 

Well the not so great Scott Atlas has left the building.
https://www.thedailybeast.com/trumps-favorite-covid-19-adviser-scott-atlas-resigns-reports?ref=home

 

""
Scott Atlas, President Trump’s special adviser on COVID-19 who pushed back on lockdowns and repeatedly downplayed the severity of the coronavirus pandemic, has submitted his resignation.

 

The neuroradiologist, who lacked expertise in infectious disease, began his 130-day position as a special government employee in August, and his gig was set to expire this week.
""

 

Hmm Resign ? Maybe looking to some future career opportunities where he can disavow his role in the policies, I resigned after all. 

 

Oh my giddy aunt as my late Nana would have said. Its a farce, or F arse....

wellygary:

 

Back of envelope says

 

66 million ppl over 2 months, = 1 million ppl per day , if there are 1000 vaccination sites, that's 1000 ppl per site/day

 

There are 1440 minutes in a 24 hr day, so its basically 1000 sites vaccinating  1 person a minute for 2 month solid, then repeat again in Feb/Mar,

 

If you had 10 vaccinators per site you are down to 100 ppl per day/site .... but you then need 100,000 trained vaccinators.....

 

 

 

They are doable numbers, but the queues would be horrendous ......

 

 

 

Lucky they're a country with a national pastime of queueing..

They changed legislation to enable many more professionals to give vaccines that weren't allowed to, and reading the UK documents the other day there is no requirement for people to wait around after a vaccination (unlike the usual recommendation for influenza vaccines) unless you're driving because there is a risk of syncope with any injection.

Digging beyond the headlines, there are some interesting caveats related to the Pfizer & Moderna effectiveness claims.

First up: https://theconversation.com/covid-19-vaccine-faq-6-things-to-look-for-in-clinical-trial-results-150843 

The Pfizer/BioNTech and Moderna studies relied on participants having symptoms and getting tested for the virus. The Oxford/AstraZeneca trial had some [?] participants regularly screened for asymptomatic infection. The different study design means it is not entirely fair to compare the percentages between trials. More information is needed before we can say anything about how these vaccines affect asymptomatic infections or transmission.

Plus (as a consequence): As discussed by Penny Ward, King’s College London in relation to the Pfizer/BioNTech vaccine “The protocol was not designed to demonstrate impact of vaccination on asymptomatic infection, or on transmission of disease from a vaccinated person to others and so the potential to use this vaccine for outbreak control cannot be estimated.” 

https://newatlas.com/health-wellbeing/moderna-covid19-vaccine-final-report-fda-eua-approval/

The same would apply equally to the Moderna vaccine. 

This also (at least partly) explains the apparently very high proportion of infected Moderna placebo cases becoming "severely ill" (#2614020); ie. 16.8% becoming "severely ill" or dying (my earlier 16.2% didn't include the death).  That is, it is 16.8% of those who became symptomatic enough to get tested. 

Still seems fairly high, unless there were higher than typical proportions of infected asymptomatic people in the placebo group.  Over the last three months only 3% - 3.5% reported cases in the US were hospitalised (plot below).  And that is for hospitalisation.  Would assume "severely ill" to be an even lower proportion, depending on their definition of "severely ill"?

UK approves Pfizer vaccine for use starting next week

https://www.bbc.com/news/health-55145696

freitasm:

 

"[Governor] Stitt declares Thursday statewide day of prayer, fasting for Oklahomans affected by coronavirus"

 

This will not end well for America. A vaccine better work well, or they are just farked.

 

Suing over being closed in some too. Sounds more like something a business losing out on funds would do rather than an organisation with morals and consideration for the people.. 

freitasm:

"[Governor] Stitt declares Thursday statewide day of prayer, fasting for Oklahomans affected by coronavirus"

This will not end well for America. A vaccine better work well, or they are just farked.

Gov. Kevin Stitt announced that he is declaring Thursday, Dec. 3 as a statewide day of prayer and fasting for all Oklahomans affected by the COVID-19 pandemic.

“Oklahomans have always turned to prayer to guide us through trials and seasons of uncertainty, and I am asking Oklahomans of all faiths and religious backgrounds to join together with me on Thursday,” said Stitt said in a news release. “I believe we must continue to ask God to heal those who are sick, comfort those who are hurting and provide renewed strength and wisdom to all who are managing the effects of COVID-19.”

 

DS248:

 

As discussed by Penny Ward, King’s College London in relation to the Pfizer/BioNTech vaccine “The protocol was not designed to demonstrate impact of vaccination on asymptomatic infection, or on transmission of disease from a vaccinated person to others and so the potential to use this vaccine for outbreak control cannot be estimated.” 

 

Surely the key thing about a vaccine is that it prevents transmission of the disease *to* a vaccinated person? That's how it impacts outbreaks. Who cares how it impacts transmission of the disease from vaccinated people, since vaccinated people, generally speaking, won't get infected?

And asymptomatic infection is not a problem (Who cares if you have the disease, if it's so trivial you don't notice it?), except (a) it's way for it to spread through the community to people who will be affected, and (b) there may be health effects some time later.

frankv:

 

...

 

And asymptomatic infection is not a problem (Who cares if you have the disease, if it's so trivial you don't notice it?), except (a) it's way for it to spread through the community to people who will be affected, and (b) there may be health effects some time later.

The "except (a) ... , and (b) ..." is the (possible) issue.   

The catch, side effects to approved Pfizer Covid-19 vaccination

A series of photos published today on The Atlantic: "The Reality of the Current Coronavirus Surge"

Two things:

1. All very sad but reality hits at #20 onwards.

2. How lucky we are that our efforts paid off so far and we don't see those images here in New Zealand.

airlines threatening to quit NZ apparently https://www.nzherald.co.nz/business/board-of-airline-representatives-says-many-air-links-to-nz-hanging-by-a-thread/IWIPF2YPQATOM3EQXKA7ZT2VVM/