I re-synced the devices (Panasonic TV, Panasonic Home Theatre, Roku 3 and Sky decoder) but still no luck. I sent the device back to the company and they replaced it with a new device....and a few months later the exact same problem. Apparently it's a fairly common fault with the hardware and no apparent fixes. Has anyone else experienced issues with this remote?
I've given up and am back to using 4 remote controls :( The 650 is an entry level product and I have no desire to spend several hundred on a top of the range universal remote, but I still expected a lot more from the remote than 3 months use.