Antique ones like FTP and rsync dont even manage to saturate a 30 meg connection when going to the other side of the world because they cant deal with the latency. At least FTP you can thread it to get better thruput.
More modern things then yes, huge difference. Have seen dropbox get pretty good speeds on a 100/50 connection, but what you are getting is the ability to have that happening while other things are happening without effecting things a lot.
I've been on 200/200 from when it became available and would not go back. VPN works great on it, especially openvpn over udp Also I am running some backups to aws buckets and glacier and can push those at around 160 to Sydney. So I say go for it
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