I have an environment which is pretty much all Microsoft in the infrastructure. It has ISA, Outlook Web Access, Exchange etc.  The Exchange server is behind the firewall and I am guessing (I am not a network guy) services are published by the ISA server which presumably is public facing. There might have to be a web server running IIS in the DMZ?

Anyway I would like to know, with this architecture, is it possible to run an application on a web server behind the firewall where the ISA server and web server in the DMZ, based on the the URL could route the traffic to the internal server?  Since ISA is able to route traffic to Exchange and also VPN traffic to the Domain Controller, both of which are behind the firewall I am guessing it's possible but really don't know for sure.

Thanks

Larry